Most of what we do—maintaining a home, raising a family, holding a job—is relatively worthwhile and culturally approved. Trouble is, everything relative involves pain, death and disappointment. We seek compensation for this through the ardent pursuit of pleasant experiences. But pleasant experiences are essentially meaningless, and eventually we find ourselves in a state of disenchantment. We wonder: What is infinitely worthwhile? Absolutely worthwhile? And we are abruptly aware that the vaunted mind cannot help us.